The outcome and quality of life of chronic myeloid leukemia (CML) patients has remarkably changed with the treatment of tyrosine kinase inhibitors (TKIs).Currently, hematopoietic stem cell transplantation (HSCT) is considered mainly as a third Wooden Toys line salvage therapy in cases of TKIs resistance or intolerance.Here we describe a patient wit

Cholesterol is an essential substance involved in many functions, such as maintaining cell membranes, manufacturing vitamin D on surface of the skin, producing hormones, and possibly helping cell connections in the brain.When cholesterol levels rise in the blood, they can, however, have dangerous consequences.In particular, cholesterol has generate

Particle impact, a new drilling technology, has been applied in drilling and gas and oil exploitation.Also, it is considerably promising as an assisting rock-breaking method for the excavation of tunnels in extremely DEEP IMMUNE KIDS hard rocks.In this paper, an experimental study was conducted to investigate the effects of particle impact number,

Single-molecule and bulk biophysical approaches to study protein-DNA interactions on surface-immobilized nucleic acid templates typically rely on modifying the ends of linear DNA molecules to enable surface-DNA attachments.Unless both strands are constrained, this results in topologically free DNA molecules and the inability to observe supercoiling

Several guidelines endorsed the indefinite use warfarin or heparin-containing products for acute venous thromboembolism (VTE) treatment and secondary prevention and discouraged the use of direct oral anticoagulants (DOAC) for patients diagnosed with antiphospholipid syndrome (APS).However, adequate anticoagulation despite warfarin therapy remains a